Mechanical Engineer, Fluidics/Perfusion
Until
•
San Francisco, CA
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Not Applicable
Posted March 26, 2026
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Responsibilities
Commitments
Responsibilities
- Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant.
- By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures.
- To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.
- We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.
Commitments
Flexible time off and paid holidays
Not Met Priorities
What still needs stronger evidence
Requirements
- Track record of exceptional engineering abilities
- Deep understanding of heat and mass transfer principles
- Experience designing fluidic systems for perfusion/heat exchangers
- High degree of autonomy across full engineering stack: electromechanical design and fabrication, control software, physical modeling
- Desire to join a fast-paced, scrappy engineering team
- 3+ years experience/graduate level in Mechanical Engineering, Physics, or equivalent
- Experience with organ perfusion in a research or clinical context
- Experience working in a startup
Preferred Skills
- 3+ years experience/graduate level in Mechanical Engineering, Physics, or equivalent
- Experience with organ perfusion in a research or clinical context
- Experience working in a startup
Education
- (Not required) – 3+ years experience/graduate level in Mechanical Engineering, Physics, or equivalent
Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures.
To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.
We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.
About You
Track record of exceptional engineering abilities
Deep understanding of heat and mass transfer principles
Experience designing fluidic systems for perfusion/heat exchangers
High degree of autonomy across full engineering stack: electromechanical design and fabrication, control software, physical modeling
Desire to join a fast-paced, scrappy engineering team
Preferred Qualifications
3+ years experience/graduate level in Mechanical Engineering, Physics, or equivalent
Experience with organ perfusion in a research or clinical context
Experience working in a startup
Benefits
Opportunity for outsized impact creating the future as an early team member
Generous medical, dental and vision insurance coverage for employees and their dependents
Flexible time off and paid holidays
Competitive compensation package, including salary and equity
Access to a 401(k) retirement savings plan
FSA and commuter benefits
Subsidized lunch daily
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
While this represents our expected range based on market data, final compensation will be determined based on your specific qualifications and may be outside this range. Please keep in mind that the equity portion of the offer is not included in this estimate.
To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.
We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.
About You
Track record of exceptional engineering abilities
Deep understanding of heat and mass transfer principles
Experience designing fluidic systems for perfusion/heat exchangers
High degree of autonomy across full engineering stack: electromechanical design and fabrication, control software, physical modeling
Desire to join a fast-paced, scrappy engineering team
Preferred Qualifications
3+ years experience/graduate level in Mechanical Engineering, Physics, or equivalent
Experience with organ perfusion in a research or clinical context
Experience working in a startup
Benefits
Opportunity for outsized impact creating the future as an early team member
Generous medical, dental and vision insurance coverage for employees and their dependents
Flexible time off and paid holidays
Competitive compensation package, including salary and equity
Access to a 401(k) retirement savings plan
FSA and commuter benefits
Subsidized lunch daily
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
While this represents our expected range based on market data, final compensation will be determined based on your specific qualifications and may be outside this range. Please keep in mind that the equity portion of the offer is not included in this estimate.