Senior Director Commercial Modernization U.S. General Medicines

Job title: Senior Director Commercial Modernization U.S. General Medicines
Location: Morristown, NJ / Cambridge, MA
About The Job
Join the team transforming how healthcare is delivered for chronic and specialty conditions worldwide. In General Medicines, you’ll help drive meaningful outcomes in diabetes, transplant, and immunology - with the scale and urgency patients deserve.
We're continuing the momentum of our key product launches and portfolio optimization to drive sustainable growth, as well as enriching our portfolio with new indications and line extensions. Our established brands and specialty products are core assets together with our mainline portfolio.
Our go-to-market transformation is progressing at pace: field sales and marketing teams are well advanced, cross-functional departments are progressing as well as we want to be holistic in our effort. To take the lead as the best in class operationally efficient and innovative organization, we must act now on areas of opportunity and continue to scan the horizon for new innovative solutions that optimize efficiencies to deliver patient impact.
About Sanofi
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.
Main Responsibilities

Serve as the NA General medicines Business Unit sponsor and value owner for execution of digital modernization roadmap across all therapeutic areas under US General Medicines, connecting with NA Go To Market Capabilities (GTMC) and Digital NA teams to establish cross-TA implementation plans with clear commercial outcomes and accountability.
Drive integrated brand planning by aligning Brands, Digital, and GTMC on a unified digital agenda across all GenMed therapeutic areas—transforming fragmented initiatives into a coordinated portfolio.
Provide commercial insights and business impact analysis to inform digital strategy and prioritization decisions, ensuring BU operational challenges, growth opportunities, and customer needs are represented in the digital roadmap.
Drive ruthless prioritization of digital initiatives, serving a strategic filter to focus resources on highest-impact opportunities that align with core business objectives.
Own the business readiness and change management strategy for digital initiatives within General Medicines U.S., ensuring organizational preparedness, stakeholder alignment, and sustainable adoption, serving as a champion to advocate for digital standards across US General Medicines.
Shape the executive business narrative on AI and digital transformation for US General Medicines by partnering with Head of Digital & NA GTMC to communicate progress, elevate AI adoption stories, and demonstrate measurable impact- building organizational confidence and momentum for continued investment.
Lead the business strategy definition in terms of AI & digital adoption within US General Medicines by identifying BU-specific cases, driving business cases development, and defining tailored learning pathways in collaboration with Sanofi Learning institutes.
Serve as the primary business voice and advocate for General Medicines U.S. commercial priorities, ensuring digital strategy and investments address BU-specific operational challenges and growth objectives.
Partnering with the Head of Digital NA and NA GTMC, translate enterprise digital strategy into actionable, BU-specific execution plans with clear accountability for commercial outcomes and measurable business impact.
Lead business process transformation and automation opportunities from a BU perspective defining success criteria and ensuring business readiness for quarterly releases delivered by GTMC and Digital. Apply deep commercial and therapeutic understanding to define automation use cases that optimize workflows across sales, HCP engagement, and patient services.
Drive adoption and sustained utilization of digital tools and AI capabilities within the Commercial Business Unit, ensuring teams are equipped to leverage technology for enhanced performance.
Identify function-specific AI/digital use cases and create role-based hands-on application opportunities that translate enterprise upskilling programs into practical commercial value.
Establish adoption metrics and feedback loops to measure capability maturity and inform continuous improvement.
Translate patient, HCP, and commercial needs, partnering with Digital and GTMC to ensure scalable solutions are designed for adoption and measurable business impact.
Lead the development of business requirements and success criteria for the digital-enabled go-to-market models across sales, HCP engagement, and direct-to-patient channels within the BU.
Represent General Medicines as the senior business stakeholder in defining requirements and validating commercial outcomes for enterprise solutions. Own the end-to-end adoption journey for digital solutions within the BU, including training, change management, performance monitoring, and iterative optimization based on user feedback and business outcomes.
Develop and present business cases, providing commercial perspective on speed, scalability, cost, and long-term value to inform build–buy–partner investment decisions.
Support assessment of AI and advanced digital solutions through a commercial lens, defining clear success criteria and organizational readiness requirements
Rigorously evaluate business value of proposed digital capabilities using defined KPIs, providing recommendations to support prioritization decisions.
Act as the General Medicines U.S. Leadership Team's primary liaison for digital execution, translating business needs into clear, prioritized requirements and owning delivery accountability within the BU.
Collaborate cross-functionally with Medical, Commercial, PSS, Marketing, Digital, GTMC, Legal, and external partners to ensure integrated planning, seamless execution and adoption.
Leverage experience across adjacent industries to bring external best practices into BU-specific digital transformation efforts.
Own the feedback loop between business users and digital teams, capturing insights on solution performance, user experience, and business impact to inform continuous improvement and future roadmap priorities.
Establish and monitor adoption metrics and business outcome KPIs, providing regular reporting to BU leadership on digital maturity, capability utilization, and value realization.
About You
Basic Qualifications:

10+ years of progressive experience in digital transformation, commercial operations, or strategic business roles within pharmaceutical, biotech, or healthcare industries
5+ years in leadership roles with demonstrated success building and executing multi-year digital strategies with measurable business impact
Proven track record leading large-scale technology modernization initiatives, including go-to-market transformations and digital automation programs
Deep understanding of pharmaceutical commercial models, including field sales, HCP engagement, and patient-centric marketing strategies
Strong therapeutic area knowledge with ability to translate clinical and patient journey insights into digital solutions
Experience managing cross-functional initiatives across Medical, Commercial, PSS, Digital/IT, Data Management, and external vendor ecosystems
Preferred Qualifications

Background in adjacent industries (Medical Devices, Healthcare Providers, Consulting, or Health Tech) with transferable best practices
Direct experience with AI/ML solution evaluation, vendor management, and technology deployment at scale
Proven track record in General Medicines, specialty pharma, or managing diverse product portfolios across multiple therapeutic areas
Experience with direct-to-patient digital channels and omnichannel engagement strategies
Consulting background with expertise in business process reengineering and organizational change management
Strong business acumen with ability to assess ROI, define value drivers, and prioritize competing investments using data-driven frameworks
Expertise in build-buy-partner decision frameworks and vendor evaluation methodologies
Knowledge of modern digital platforms, automation technologies, CRM systems, and data analytics tools used in pharmaceutical commercialization
Understanding of AI, machine learning, and emerging technologies with ability to translate innovation into practical business applications
Proficiency in agile delivery methodologies and quarterly release planning
Exceptional strategic thinking with ability to translate complex business needs into clear, actionable digital requirements
Strong executive presence and communication skills to influence senior leadership and drive organizational alignment
Proven ability to lead through influence in matrixed organizations without direct authority
Change management expertise with track record of driving adoption of new technologies and ways of working
Collaborative leadership style with ability to build trust across diverse stakeholder groups
Entrepreneurial mindset with bias for action and ability to deliver tangible results in fast-paced environments
Balance of strategic vision and operational execution—comfortable moving from 30,000-foot strategy to hands-on problem solving
Comfort with ambiguity and the ability to build new capabilities from the ground up
Patient-centric orientation with commitment to improving healthcare outcomes through digital innovation.
Travel

Approximately 25 percent to 30 percent.
Education

Bachelor's degree required; Advanced degree (MBA, MS, or equivalent) strongly preferred
Why Choose Us?

Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or a lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs, and at least 14 weeks’ gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.