Postdoctoral Fellow – Molecular Mechanisms of Neurodegeneration, Bingol Lab
Genentech
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South San Francisco, CA
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Entry level
Posted March 13, 2026
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Responsibilities
Commitments
Responsibilities
- This position will center on elucidating the molecular mechanisms of lysosomal and mitochondrial quality control in the context of neurodegenerative diseases, including Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis.
- The successful candidate will leverage cutting-edge technologies—including proteomics, lipidomics, next-generation sequencing, CRISPR, iPSC-derived and primary culture models, in vivo systems, and AI/ML-supported computational biology—to uncover fundamental disease mechanisms.
- Collaborate productively with researchers across departments, present your work to project teams, and publish as first author on scientific publications.
- Join a vibrant Neuroscience community that includes leaders in discovering the molecular causes and therapeutic targets for neurodegenerative diseases.
- Participate in the Genentech Postdoctoral Program, which provides an exceptional environment for pursuing fundamental scientific questions and driving breakthrough discoveries.
- Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering.
Commitments
Relocation benefits are available for this job posting.
Not Met Priorities
What still needs stronger evidence
Requirements
- Must have advanced at least one key research project focusing on mechanistic research, as evidenced by a first-author paper published or accepted in a leading peer-reviewed journal.
- An independent, resilient scientist with outstanding communication skills and a strong intrinsic drive, who thrives in a collaborative team environment.
- Motivated by identifying novel therapeutic targets for neurodegenerative diseases.
- Proven track record of success in wet-laboratory experimentation.
- Working knowledge of large-scale data analysis (e.g., RNA-seq, proteomics).
Preferred Skills
- Hands-on experience with iPSC-based cultures of CNS cell types, primary rodent cultures, and genetic perturbation methods.
- Deep understanding of molecular mechanisms relevant to neurodegeneration, particularly mitochondrial or lysosomal pathways.
- Proven track record of success in wet-laboratory experimentation.
- Working knowledge of large-scale data analysis (e.g., RNA-seq, proteomics).
- Excellent data organization, presentation, and communication skills.
- For more information about the Bingol Lab, please see link below:
Education
- (Not required) – Ph.D. in a relevant field with a strong track record of excellence in cellular and molecular neuroscience.
- (Required) – Must have advanced at least one key research project focusing on mechanistic research, as evidenced by a first-author paper published or accepted in a leading peer-reviewed journal.
The Position
A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech.
A postdoctoral fellow position is available for a highly motivated and independent scientist to join the laboratory of Baris Bingol in the Department of Neuroscience at Genentech. The Bingol lab investigates the molecular mechanisms of neurodegeneration, with a particular focus on neuronal and glial proteostasis. This position will center on elucidating the molecular mechanisms of lysosomal and mitochondrial quality control in the context of neurodegenerative diseases, including Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis.
This fellowship offers a unique opportunity to contribute to target discovery efforts and to perform mechanistic studies to understand how human genetic variants disrupt organelle and protein quality control pathways. Candidates with a strong track record in mechanistic molecular and cellular neurobiology research are encouraged to apply. The successful candidate will leverage cutting-edge technologies—including proteomics, lipidomics, next-generation sequencing, CRISPR, iPSC-derived and primary culture models, in vivo systems, and AI/ML-supported computational biology—to uncover fundamental disease mechanisms.
The Opportunity
Collaborate productively with researchers across departments, present your work to project teams, and publish as first author on scientific publications.
Join a vibrant Neuroscience community that includes leaders in discovering the molecular causes and therapeutic targets for neurodegenerative diseases.
Participate in the Genentech Postdoctoral Program, which provides an exceptional environment for pursuing fundamental scientific questions and driving breakthrough discoveries.
Who You Are
Ph.D. in a relevant field with a strong track record of excellence in cellular and molecular neuroscience.
Must have advanced at least one key research project focusing on mechanistic research, as evidenced by a first-author paper published or accepted in a leading peer-reviewed journal.
An independent, resilient scientist with outstanding communication skills and a strong intrinsic drive, who thrives in a collaborative team environment.
Motivated by identifying novel therapeutic targets for neurodegenerative diseases.
Preferred Qualifications
Hands-on experience with iPSC-based cultures of CNS cell types, primary rodent cultures, and genetic perturbation methods.
Deep understanding of molecular mechanisms relevant to neurodegeneration, particularly mitochondrial or lysosomal pathways.
Proven track record of success in wet-laboratory experimentation.
Working knowledge of large-scale data analysis (e.g., RNA-seq, proteomics).
Excellent data organization, presentation, and communication skills.
For more information about the Bingol Lab, please see link below:
https://www.gene.com/scientists/our-scientists/baris-bingol
The expected salary range for this position based on the primary location of California is $98,000 to $104,500 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Relocation benefits are available for this job posting.
Postdoc Program
Elevate your research career to new heights with Genetech’s Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions.
The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader.
The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to the Genentech Postdoctoral Program and unlock your full potential!
#postdoc
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech.
A postdoctoral fellow position is available for a highly motivated and independent scientist to join the laboratory of Baris Bingol in the Department of Neuroscience at Genentech. The Bingol lab investigates the molecular mechanisms of neurodegeneration, with a particular focus on neuronal and glial proteostasis. This position will center on elucidating the molecular mechanisms of lysosomal and mitochondrial quality control in the context of neurodegenerative diseases, including Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis.
This fellowship offers a unique opportunity to contribute to target discovery efforts and to perform mechanistic studies to understand how human genetic variants disrupt organelle and protein quality control pathways. Candidates with a strong track record in mechanistic molecular and cellular neurobiology research are encouraged to apply. The successful candidate will leverage cutting-edge technologies—including proteomics, lipidomics, next-generation sequencing, CRISPR, iPSC-derived and primary culture models, in vivo systems, and AI/ML-supported computational biology—to uncover fundamental disease mechanisms.
The Opportunity
Collaborate productively with researchers across departments, present your work to project teams, and publish as first author on scientific publications.
Join a vibrant Neuroscience community that includes leaders in discovering the molecular causes and therapeutic targets for neurodegenerative diseases.
Participate in the Genentech Postdoctoral Program, which provides an exceptional environment for pursuing fundamental scientific questions and driving breakthrough discoveries.
Who You Are
Ph.D. in a relevant field with a strong track record of excellence in cellular and molecular neuroscience.
Must have advanced at least one key research project focusing on mechanistic research, as evidenced by a first-author paper published or accepted in a leading peer-reviewed journal.
An independent, resilient scientist with outstanding communication skills and a strong intrinsic drive, who thrives in a collaborative team environment.
Motivated by identifying novel therapeutic targets for neurodegenerative diseases.
Preferred Qualifications
Hands-on experience with iPSC-based cultures of CNS cell types, primary rodent cultures, and genetic perturbation methods.
Deep understanding of molecular mechanisms relevant to neurodegeneration, particularly mitochondrial or lysosomal pathways.
Proven track record of success in wet-laboratory experimentation.
Working knowledge of large-scale data analysis (e.g., RNA-seq, proteomics).
Excellent data organization, presentation, and communication skills.
For more information about the Bingol Lab, please see link below:
https://www.gene.com/scientists/our-scientists/baris-bingol
The expected salary range for this position based on the primary location of California is $98,000 to $104,500 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Relocation benefits are available for this job posting.
Postdoc Program
Elevate your research career to new heights with Genetech’s Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions.
The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader.
The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to the Genentech Postdoctoral Program and unlock your full potential!
#postdoc
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.