Postdoctoral Fellow - AI/ML for Immunology, Vander Heiden Lab
Genentech
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South San Francisco, CA
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Entry level
Posted March 13, 2026
Job link
Thinking about this job
Responsibilities
Commitments
Responsibilities
- You will focus on training and applying AI/ML models to questions in adaptive immunity, such as classification of patient immune set points, inferring immunological history from adaptive immune receptor receptors (AIRR), and understanding B and T cell repertoire dynamics in health and disease.
- You will also work closely with colleagues in the Immunology Discovery department to identify opportunities to generate meaningful training data and collaborate on applications of the methods developed during the postdoc’s tenure.
- Work closely with computational colleagues to build, train, and evaluate cutting edge AI/ML models to investigate immune states across health and disease.
- Focus on innovation and exploratory AI/ML research within a data-rich environment.
- Technical and scientific mentorship from computational and experimental colleagues.
- Present at external scientific conferences and publish insights in high-impact journals.
Commitments
Relocation benefits are available for this job posting.
About Genentech’s Postdoctoral Program:
The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network.
By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Not Met Priorities
What still needs stronger evidence
Requirements
- Proficiency with multiple AI model architectures (e.g., transformers, MIL, GANs, GNNs) and explainability frameworks (e.g., integrated gradients).
- Experience with both analysis and computational method development for single-cell RNA-seq and AIRR-seq (BCR or TCR).
- Experience with python, machine learning libraries, version control, containerization, and high-performance compute environments.
- Ability to clearly and effectively communicate complex AI/ML approaches to both computation and experimental audiences.
- A history of high-impact, first-author publications in AI/ML, bioinformatics, or immunology topic areas.
- Independent, highly motivated, and highly collaborative with the ability to work together with multi-disciplinary teams of computational and experimental scientists.
Preferred Skills
- Ph.D. in Computational Biology, Bioinformatics, Computer Science or Machine Learning related field
- Experience with both analysis and computational method development for single-cell RNA-seq and AIRR-seq (BCR or TCR).
- A history of high-impact, first-author publications in AI/ML, bioinformatics, or immunology topic areas.
Education
- (Not required) – Ph.D. in Computational Biology, Bioinformatics, Computer Science or Machine Learning related field
The Position
We advance science so that we all have more time with the people we love.
A Postdoctoral Fellow position is available in the Vander Heiden Lab of the Biological Research AI Development (BRAID) group within the AI for Biology & Translation (AIBT) Department. BRAID/AIBT is an innovation center focused on developing and applying novel AI/ML approaches to biological data.
You will focus on training and applying AI/ML models to questions in adaptive immunity, such as classification of patient immune set points, inferring immunological history from adaptive immune receptor receptors (AIRR), and understanding B and T cell repertoire dynamics in health and disease. You will also work closely with colleagues in the Immunology Discovery department to identify opportunities to generate meaningful training data and collaborate on applications of the methods developed during the postdoc’s tenure.
The Opportunity:
Work closely with computational colleagues to build, train, and evaluate cutting edge AI/ML models to investigate immune states across health and disease.
Focus on innovation and exploratory AI/ML research within a data-rich environment.
Technical and scientific mentorship from computational and experimental colleagues.
Present at external scientific conferences and publish insights in high-impact journals.
Who You Are:
Ph.D. in Computational Biology, Bioinformatics, Computer Science or Machine Learning related field
Proficiency with multiple AI model architectures (e.g., transformers, MIL, GANs, GNNs) and explainability frameworks (e.g., integrated gradients).
Experience with both analysis and computational method development for single-cell RNA-seq and AIRR-seq (BCR or TCR).
Experience with python, machine learning libraries, version control, containerization, and high-performance compute environments.
Ability to clearly and effectively communicate complex AI/ML approaches to both computation and experimental audiences.
A history of high-impact, first-author publications in AI/ML, bioinformatics, or immunology topic areas.
Independent, highly motivated, and highly collaborative with the ability to work together with multi-disciplinary teams of computational and experimental scientists.
The expected salary range for this position based on the primary location of California is $110,000 to $120,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Relocation benefits are available for this job posting.
About Genentech’s Postdoctoral Program:
Elevate your research career to new heights with Genetech’s Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions.
The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech’s Postdoctoral Program and unlock your full potential!
#postdoc
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
We advance science so that we all have more time with the people we love.
A Postdoctoral Fellow position is available in the Vander Heiden Lab of the Biological Research AI Development (BRAID) group within the AI for Biology & Translation (AIBT) Department. BRAID/AIBT is an innovation center focused on developing and applying novel AI/ML approaches to biological data.
You will focus on training and applying AI/ML models to questions in adaptive immunity, such as classification of patient immune set points, inferring immunological history from adaptive immune receptor receptors (AIRR), and understanding B and T cell repertoire dynamics in health and disease. You will also work closely with colleagues in the Immunology Discovery department to identify opportunities to generate meaningful training data and collaborate on applications of the methods developed during the postdoc’s tenure.
The Opportunity:
Work closely with computational colleagues to build, train, and evaluate cutting edge AI/ML models to investigate immune states across health and disease.
Focus on innovation and exploratory AI/ML research within a data-rich environment.
Technical and scientific mentorship from computational and experimental colleagues.
Present at external scientific conferences and publish insights in high-impact journals.
Who You Are:
Ph.D. in Computational Biology, Bioinformatics, Computer Science or Machine Learning related field
Proficiency with multiple AI model architectures (e.g., transformers, MIL, GANs, GNNs) and explainability frameworks (e.g., integrated gradients).
Experience with both analysis and computational method development for single-cell RNA-seq and AIRR-seq (BCR or TCR).
Experience with python, machine learning libraries, version control, containerization, and high-performance compute environments.
Ability to clearly and effectively communicate complex AI/ML approaches to both computation and experimental audiences.
A history of high-impact, first-author publications in AI/ML, bioinformatics, or immunology topic areas.
Independent, highly motivated, and highly collaborative with the ability to work together with multi-disciplinary teams of computational and experimental scientists.
The expected salary range for this position based on the primary location of California is $110,000 to $120,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Relocation benefits are available for this job posting.
About Genentech’s Postdoctoral Program:
Elevate your research career to new heights with Genetech’s Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions.
The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech’s Postdoctoral Program and unlock your full potential!
#postdoc
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.